What is PSA and Why Can it be Elevated?

PSA (Prostate-Specific Antigen) is a protein produced by both normal and cancerous prostate cells. A blood test measures PSA levels to assess prostate health. While PSA can be a sign of prostate cancer, many non-cancerous factors can raise it:

  • Benign Prostatic Hyperplasia (BPH) — non-cancerous enlargement
  • Prostatitis — inflammation or infection
  • Urinary tract infection
  • Recent ejaculation or vigorous exercise (especially cycling)
  • Recent urologic procedures or catheter use
  • Prostate cancer

Why Advanced Evaluation Matters

A single elevated PSA does not mean cancer — but it does mean we should look deeper. Our team specializes in distinguishing benign causes from those needing treatment, using the most accurate diagnostics available to minimize unnecessary biopsies and target treatment when needed.

Advanced Testing at Advanced Urology

  • Repeat PSA with free-to-total PSA ratio to refine risk
  • IsoPSA and 4Kscore® to estimate risk of aggressive cancer
  • Multiparametric MRI to identify suspicious lesions
  • MRI/Ultrasound fusion-guided biopsy for precise targeting
  • Genomic testing on biopsy tissue if cancer is found
  • Streamlined results review and individualized plan

State-of-the-Art Surgical Centers

  • Diagnostics and procedures performed in our advanced ambulatory surgery centers
  • Full anesthesia — not light sedation — for maximum comfort
  • No pain during procedures
  • Expert team with unmatched experience in prostate diagnostics and care

What to Expect

If your PSA is elevated, we’ll review your history, discuss possible causes, and guide you through a comprehensive evaluation. With MRI-fusion technology and advanced surgical navigation, we detect clinically significant prostate cancer with high accuracy — and avoid unnecessary biopsies whenever possible.

Next Step

If your PSA is elevated, schedule a consultation with Advanced Urology (Atlanta, GA). With leading-edge technology, expert care, and world-class facilities, we provide the most comfortable and accurate evaluation possible.

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